O,O-diethyl (fluoromethyl)phosphonate
diethyl (fluoromethyl)phosphonate
CAS: 96857-55-5
Molecular Formula: C5H12FO3P
O,O-diethyl (fluoromethyl)phosphonate - Names and Identifiers
O,O-diethyl (fluoromethyl)phosphonate - Physico-chemical Properties
| Molecular Formula | C5H12FO3P |
| Molar Mass | 170.12 |
| Density | 1.109g/cm3 |
| Boling Point | 195.2°C at 760 mmHg |
| Flash Point | 71.9°C |
| Vapor Presure | 0.594mmHg at 25°C |
| Refractive Index | 1.382 |
O,O-diethyl (fluoromethyl)phosphonate - Introduction
diethyl (fluoromethyl)phosphonate is an organic compound with the chemical formula C6H13FO3P. Its nature, use, formulation and safety information are described below.
Nature:
diethyl (fluoromethyl)phosphonate is a colorless to pale yellow liquid with a special odor. It has a low boiling point and melting point, soluble in organic solvents such as ethanol, ether and hydrocarbon solvents, insoluble in water.
Use:
diethyl (fluoromethyl)phosphonate are widely used in organic synthesis. It can be used as a reagent and intermediate, and plays an important role in the synthesis of pesticides, drugs, dyes and other organic compounds. For example, it can be used to synthesize phosphate antiepileptic drugs, antiviral drugs and anti-tumor drugs.
Preparation Method:
diethyl (fluoromethyl)phosphonate can be prepared by reacting fluorinated methyl alcohol with diethyl trimethylphosphonate. In the specific operation, the fluorinated methyl alcohol and diethyl trimethylphosphonate are placed in a reaction bottle, and an appropriate amount of alkali catalyst such as tripropylamine is added, and the target product is obtained after the reaction.
Safety Information:
diethyl (fluoromethyl)phosphonate belong to organic phosphorus compounds, and they need to be safe during use and storage. It can be irritating and corrosive to the eyes, skin and respiratory tract, so always wear protective gloves, goggles and clothing when in contact. In addition, it should be used in a well-ventilated place and avoid inhalation or ingestion. If inhaled or in contact with skin or eyes, rinse immediately with plenty of water and seek medical help. When stored, it should be kept in a sealed container, away from fire and oxidizing agents.
Nature:
diethyl (fluoromethyl)phosphonate is a colorless to pale yellow liquid with a special odor. It has a low boiling point and melting point, soluble in organic solvents such as ethanol, ether and hydrocarbon solvents, insoluble in water.
Use:
diethyl (fluoromethyl)phosphonate are widely used in organic synthesis. It can be used as a reagent and intermediate, and plays an important role in the synthesis of pesticides, drugs, dyes and other organic compounds. For example, it can be used to synthesize phosphate antiepileptic drugs, antiviral drugs and anti-tumor drugs.
Preparation Method:
diethyl (fluoromethyl)phosphonate can be prepared by reacting fluorinated methyl alcohol with diethyl trimethylphosphonate. In the specific operation, the fluorinated methyl alcohol and diethyl trimethylphosphonate are placed in a reaction bottle, and an appropriate amount of alkali catalyst such as tripropylamine is added, and the target product is obtained after the reaction.
Safety Information:
diethyl (fluoromethyl)phosphonate belong to organic phosphorus compounds, and they need to be safe during use and storage. It can be irritating and corrosive to the eyes, skin and respiratory tract, so always wear protective gloves, goggles and clothing when in contact. In addition, it should be used in a well-ventilated place and avoid inhalation or ingestion. If inhaled or in contact with skin or eyes, rinse immediately with plenty of water and seek medical help. When stored, it should be kept in a sealed container, away from fire and oxidizing agents.
Last Update：2024-04-09 20:52:54
